Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | GUSB | P08236 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1144864 | 0.80 | PIN1 (0.63) | KDM4EALDH1A1DAOTSHRKMT2A | |
| SCHEMBL10969986 | 0.80 | KDM4E (0.66) | KDM4EALDH1A1GAAPOLBDAO | |
| SCHEMBL31222309 | 0.78 | ALDH1A1 (0.72) | KDM4EALDH1A1GAAPOLBTSHR | |
| SCHEMBL29415468 | 0.78 | KDM4E (0.63) | KDM4EALDH1A1GAAPOLBHSD17B10 | |
| SCHEMBL2806050 | 0.78 | KDM4E (0.63) | KDM4EALDH1A1GAAPOLBHSD17B10 | |
| SCHEMBL31272773 | 0.77 | DAO (0.51) | KDM4EALDH1A1GAAPOLBDAO | |
| SCHEMBL11142199 | 0.76 | KDM4E (0.61) | KDM4EALDH1A1GAAPOLBKMT2A | |
| SCHEMBL8500109 | 0.76 | KDM4E (0.63) | KDM4EALDH1A1GAAPOLBDAO | |
| SCHEMBL2310250 | 0.76 | F7 (0.63) | KDM4EALDH1A1GAAPOLBDAO | |
| SCHEMBL2310539 | 0.76 | KDM4E (0.61) | KDM4EALDH1A1GAAPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705297-A1 | SMALL MOLECULE THERAPY FOR DUCHENNE MUSCULAR DYSTROPHY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024229205-A1 | SMALL MOLECULE THERAPY FOR DUCHENNE MUSCULAR DYSTROPHY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-11-07 | — | — | WO | disclosed |