Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | TACR1 | P25103 | 2/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31228189 | 1.00 | MMP3 (0.31) | MMP3ADAM17KMT2APTPN1EPHX1 | |
| SCHEMBL31228362 | 1.00 | MMP3 (0.31) | MMP3ADAM17KMT2APTPN1EPHX1 | |
| SCHEMBL31228414 | 0.91 | KMT2A (0.32) | MMP3ADAM17KMT2ATACR1 | |
| SCHEMBL31228376 | 0.83 | MMP13 (0.38) | MMP3KMT2AHCRTR2 | |
| SCHEMBL31228461 | 0.78 | ALDH1A1 (0.30) | KMT2A | |
| SCHEMBL31228607 | 0.76 | ATM (0.31) | KMT2A | |
| SCHEMBL31228409 | 0.75 | — | — | |
| SCHEMBL31153653 | 0.75 | NR1H2 (0.30) | — | |
| SCHEMBL31228575 | 0.74 | MEN1 (0.33) | KMT2A | |
| SCHEMBL31228349 | 0.73 | CA14 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4688789-A1 | MACROCYCLIC RAS INHIBITORS | Revolution Medicines, Inc. (US) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024211663-A9 | MACROCYCLIC RAS INHIBITORS | Revolution Medicines, Inc. (US) | 2025-01-30 | — | — | WO | disclosed |
| WO-2024211663-A1 | CONDENSED MACROCYCLIC COMPOUNDS AS RAS INHIBITORS | Revolution Medicines, Inc. (US) | 2024-10-10 | — | — | WO | disclosed |