Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.61 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | DPP4 | P27487 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2548401 | 0.76 | PIM1 (1.00) | PIM1ENPP2AKR1B1SMN1; SMN2MEN1 | |
| SCHEMBL2548399 | 0.76 | PIM1 (1.00) | PIM1ENPP2AKR1B1SMN1; SMN2MEN1 | |
| SCHEMBL14560445 | 0.75 | MAOA (0.65) | MAOAMAOBNPC1LMNARAB9A | |
| SCHEMBL4207901 | 0.74 | AKR1B1 (0.59) | PIM1ENPP2MAOAMAOBPTPN1 | |
| SCHEMBL4207906 | 0.74 | AKR1B1 (0.59) | PIM1ENPP2MAOAMAOBPTPN1 | |
| SCHEMBL20534356 | 0.74 | AKR1B1 (0.78) | PTPN1AKR1B1MAPT | |
| SCHEMBL20534357 | 0.74 | AKR1B1 (0.78) | PTPN1AKR1B1MAPT | |
| SCHEMBL6691625 | 0.73 | PPARG (0.69) | PIM1ENPP2PTPN1LMNAL3MBTL1 | |
| SCHEMBL6691628 | 0.73 | PPARG (0.69) | PIM1ENPP2PTPN1LMNAL3MBTL1 | |
| SCHEMBL13446896 | 0.73 | MMP1 (0.73) | MAOAMAOBFFAR1NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12150935-B1 | 3-(3-(1,3-dioxoisoindolin-2-yl) propyl)-5-(4-fluorobenzylidene) thiazolidine-2,4-dione as a potential antitumor and apoptotic inducer | IMAM MOHAMMAD IBN SAUD ISLAMIC UNIVERSITY (SA) | 2024-11-26 | — | — | US | disclosed |
| US-12150935-B1 | 3-(3-(1,3-dioxoisoindolin-2-yl) propyl)-5-(4-fluorobenzylidene) thiazolidine-2,4-dione as a potential antitumor and apoptotic inducer | IMAM MOHAMMAD IBN SAUD ISLAMIC UNIVERSITY (SA) | 2024-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12150935-B1 | 3-(3-(1,3-dioxoisoindolin-2-yl) propyl)-5-(4-fluorobenzylidene) thiazolidine-2,4-dione as a potential antitumor and apoptotic inducer | MCL1, CASP3, ACIN1 | PIM1 1227/4885ENPP2 3293/4885MAOA 4664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.