Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 6/20 | 0.58 |
| ▸ | NPY1R | P25929 | 1/20 | 0.55 |
| ▸ | NPY2R | P49146 | 1/20 | 0.55 |
| ▸ | NPY4R | P50391 | 1/20 | 0.55 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.55 |
| ▸ | CTSL | P07711 | 3/20 | 0.55 |
| ▸ | CTSS | P25774 | 3/20 | 0.55 |
| ▸ | CTSK | P43235 | 3/20 | 0.55 |
| ▸ | CTSH | P09668 | 1/20 | 0.55 |
| ▸ | CCKBR | P32239 | 3/20 | 0.54 |
| ▸ | CCKAR | P32238 | 1/20 | 0.54 |
| ▸ | CXCL8 | P10145 | 5/20 | 0.53 |
| ▸ | DPP3 | Q9NY33 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30343341 | 0.91 | DPP3 (0.55) | CXCR4NPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL31235881 | 0.89 | DPP3 (0.57) | CXCR4CCKBRCCKARCXCL8DPP3 | |
| SCHEMBL30512541 | 0.88 | CTSL (0.61) | CXCR4NPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL29412263 | 0.88 | CXCR4 (0.61) | CXCR4NPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL30273393 | 0.88 | CXCR4 (0.61) | CXCR4NPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL31001651 | 0.87 | CXCR4 (0.59) | CXCR4NPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL31665985 | 0.87 | CXCR4 (0.64) | CXCR4NPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL30735734 | 0.86 | CXCR4 (0.58) | CXCR4CTSLCTSSCTSKCTSH | |
| SCHEMBL29845535 | 0.86 | CXCR4 (0.60) | CXCR4NPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL30381291 | 0.86 | KISS1R (0.56) | CXCR4CTSLCTSSCTSKCTSH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240376517-A1 | GRANZYME B DETECTION | THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) | 2024-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240376517-A1 | GRANZYME B DETECTION | GZMB, CTSB, DNASE1L3 | CXCR4 1513/4885NPY1R 1620/4885NPY2R 1821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.