SCHEMBL31237286

SCHEMBL31237286

O=C1CCC2C3CC4C5(CC[N+]4([O-])C/C3=C\CO)c3ccccc3N1C25

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GLRA1 P23415 2/20 0.39
GLRB P48167 2/20 0.39
CHRNA7 P36544 7/20 0.39
CHRM2 P08172 3/20 0.37
CHRNA4 P43681 1/20 0.37
KCNH2 Q12809 1/20 0.37
HTR3A P46098 5/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30553694 0.60 GLRA1 (0.56) GLRA1GLRBCHRNA7HTR3A
Isostrychnine SCHEMBL29898321 0.56 CHRNA7 (0.43) GLRA1GLRBCHRNA7CHRM2CHRNA4
Hydrochloric Acid SCHEMBL31650965 0.56 CHRNA7 (1.00) CHRNA7CHRM2CHRNA4KCNH2HTR3A
Alcuronium SCHEMBL122972 0.54 CHRNA7 (0.98) CHRNA7CHRM2CHRNA4KCNH2HTR3A
SCHEMBL17501926 0.49 PTGER2 (0.44)
SCHEMBL16096237 0.49 PTGER2 (0.44)
SCHEMBL29079061 0.48 MEN1 (0.42)
SCHEMBL16102918 0.46 HTR7 (0.44)
SCHEMBL16102919 0.46 HTR7 (0.44)
SCHEMBL8883664 0.46 ALDH1A1 (0.56) CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024189607-A1 METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR DISEASES TREATMENT DIDENKO KIRILL (MX) 2024-09-19 WO disclosed