Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7340898 | 0.79 | LMNA (0.76) | ALDH1A1LMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL20243989 | 0.72 | LMNA (0.43) | ALDH1A1LMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9369348 | 0.69 | LMNA (0.71) | ALDH1A1LMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9365369 | 0.65 | ALDH1A1 (0.68) | ALDH1A1LMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4429170 | 0.65 | LMNA (0.67) | ALDH1A1LMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11803025 | 0.62 | ALDH1A1 (0.39) | ALDH1A1LMNAKMT2AMEN1KDM4E | |
| SCHEMBL17199569 | 0.62 | BRD4 (0.38) | ALDH1A1LMNAKMT2AMEN1KDM4E | |
| SCHEMBL1760639 | 0.58 | NOTUM (0.52) | LMNAKMT2ANOTUMHSD17B10MTNR1A | |
| SCHEMBL8342494 | 0.58 | LMNA (0.75) | ALDH1A1LMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7527942 | 0.57 | HDAC3 (0.63) | LMNAKMT2AMEN1SMN1; SMN2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024189607-A1 | METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR DISEASES TREATMENT | DIDENKO KIRILL (MX) | 2024-09-19 | — | — | WO | disclosed |