Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CPS1 | P31327 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7340898 | 0.81 | LMNA (0.76) | LMNAALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8342323 | 0.72 | LMNA (0.72) | LMNAALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4429170 | 0.72 | LMNA (0.67) | LMNAALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9369302 | 0.70 | LMNA (0.78) | LMNAALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9365765 | 0.70 | LMNA (0.44) | LMNAALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL31237847 | 0.69 | ALDH1A1 (0.53) | LMNAALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9366661 | 0.68 | ALDH1A1 (0.64) | LMNAALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8342494 | 0.68 | LMNA (0.75) | LMNAALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8342786 | 0.67 | LMNA (0.68) | LMNAALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8343305 | 0.67 | LMNA (0.68) | LMNAALDH1A1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579695-A1 | REISSERT COMPOUNDS AS ANTI-HIV AGENTS | THE UPJOHN COMPANY (US) | 1994-01-26 | — | — | EP | claimed |
| WO-1992016508-A1 | REISSERT COMPOUNDS AS ANTI-HIV AGENTS | THE UPJOHN COMPANY (US) | 1992-10-01 | — | — | WO | claimed |
| EP-0579695-A1 | REISSERT COMPOUNDS AS ANTI-HIV AGENTS | THE UPJOHN COMPANY (US) | 1994-01-26 | — | — | EP | disclosed |
| WO-1992016508-A1 | REISSERT COMPOUNDS AS ANTI-HIV AGENTS | THE UPJOHN COMPANY (US) | 1992-10-01 | — | — | WO | disclosed |