Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.76 |
| ▸ | MEN1 | O00255 | 3/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9366677 | 0.86 | ALDH1A1 (1.00) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6195822 | 0.85 | LMNA (1.00) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8345917 | 0.82 | LMNA (0.78) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8342494 | 0.81 | LMNA (0.75) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9369348 | 0.81 | LMNA (0.71) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL31237847 | 0.79 | ALDH1A1 (0.53) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9365701 | 0.77 | LMNA (0.79) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9369302 | 0.76 | LMNA (0.78) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4429170 | 0.75 | LMNA (0.67) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9365654 | 0.74 | LMNA (0.71) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0699680-B1 | Oxazoloquinolinone derivatives, their preparation and their use in therapy | SANOFI SYNTHELABO (FR) | 2000-03-08 | — | — | EP | disclosed |
| US-5641785-A | ANTIDEPRESSANTS, NERVOUS SYSTEM DISORDERS | SYNTHELABO (FR) | 1997-06-24 | — | — | US | disclosed |
| EP-0699680-A1 | Oxazoloquinolinone derivatives, their preparation and their use in therapy | SYNTHELABO (FR) | 1996-03-06 | — | — | EP | disclosed |