Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | WNT3A | P56704 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | F11 | P03951 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | TTK | P33981 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.39 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.39 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240445 | 0.87 | WNT3A (0.47) | CDK2WNT3AMEN1KMT2AF11 | |
| SCHEMBL31240493 | 0.86 | WNT3A (0.57) | CDK2WNT3AMEN1KMT2AF11 | |
| SCHEMBL31240382 | 0.85 | MAPK1 (0.52) | CDK2WNT3AGSK3BROCK1 | |
| SCHEMBL31240463 | 0.85 | PSEN1 (0.54) | CDK2WNT3AMEN1KMT2AJAK2 | |
| SCHEMBL31240399 | 0.85 | JAK2 (0.54) | CDK2WNT3AF11JAK2RIOK2 | |
| SCHEMBL31240402 | 0.85 | ROCK1 (0.54) | CDK2WNT3AROCK1RIOK2 | |
| SCHEMBL31240538 | 0.83 | DYRK1A (0.52) | WNT3AMEN1KMT2AMAPTRIOK2 | |
| SCHEMBL31240563 | 0.82 | DYRK1A (0.51) | WNT3AJAK2GSK3B | |
| SCHEMBL31240675 | 0.82 | WNT3A (0.52) | CDK2WNT3AMEN1KMT2AJAK2 | |
| SCHEMBL31240509 | 0.82 | JAK2 (0.56) | CDK2WNT3AMEN1KMT2AJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | claimed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | claimed |
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |