Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K11 | Q16584 | 2/20 | 0.41 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.41 |
| ▸ | CDC7 | O00311 | 2/20 | 0.41 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 2/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.40 |
| ▸ | MARK3 | P27448 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.40 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | PKN2 | Q16513 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240380 | 0.86 | CLK2 (0.41) | MAP3K11CDC7CDK1CDK2DYRK1A | |
| SCHEMBL31240648 | 0.80 | TRPA1 (0.41) | CDK2DYRK1AGSK3BCDK5CCNK | |
| SCHEMBL31240722 | 0.79 | CDK9 (0.56) | CDC7CDK1CDK2CCNKCDK12 | |
| SCHEMBL31240291 | 0.78 | DYRK1A (0.43) | DYRK1ATBK1CSNK1DCLK2CLK3 | |
| SCHEMBL31240749 | 0.78 | DYRK1A (0.44) | MAP3K11CDK1CDK2DYRK1ACCNK | |
| SCHEMBL31240676 | 0.78 | CDK9 (0.39) | CDC7CDK1CDK2DYRK1ACCNK | |
| SCHEMBL31240731 | 0.74 | ROCK2 (0.44) | MAP3K11TNIKROCK2ROCK1CDC42BPB | |
| SCHEMBL31240766 | 0.73 | AURKA (0.47) | DYRK1AAURKACCNKCDK12TBK1 | |
| SCHEMBL31240393 | 0.70 | CCNT1 (0.38) | ROCK2CDC7CDK2DYRK1AAURKA | |
| SCHEMBL31240412 | 0.67 | CLK2 (0.51) | DYRK1AEGFRCLK2CLK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | claimed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | claimed |