Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 5/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21723650 | 0.87 | ALDH1A1 (0.55) | NPSR1GAAPOLBSMN1; SMN2TSHR | |
| SCHEMBL23542681 | 0.78 | TP53 (0.59) | GAAPOLBSMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL31248428 | 0.78 | USP2 (0.46) | NPSR1GAASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL1374250 | 0.77 | ALDH1A1 (0.47) | GAAALDH1A1TP53MAPTHPGD | |
| SCHEMBL2346864 | 0.76 | GAA (0.77) | NPSR1GAAPOLBSMN1; SMN2TSHR | |
| SCHEMBL23919240 | 0.76 | KMT2A (0.51) | GAATSHRKMT2A | |
| SCHEMBL7779173 | 0.75 | NPSR1 (0.66) | NPSR1GAAPOLBSMN1; SMN2TSHR | |
| SCHEMBL11815554 | 0.74 | GAA (0.72) | NPSR1GAAPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL23732506 | 0.73 | GAA (0.55) | GAASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL31248447 | 0.73 | CA12 (0.44) | POLBTSHRALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12234207-B2 | Halo-(3-(phenylsulfonyl)prop-1-enyl)pyridine derivative and use thereof | CUREVERSE INCORPORATED (KR) | 2025-02-25 | — | — | US | disclosed |
| US-20210317083-A1 | NOVEL HALO-(3-(PHENYLSULFONYL)PROP-1-ENYL)PYRIDINE DERIVATIVE AND USE THEREOF | CUREVERSE INCORPORATED (KR) | 2021-10-14 | — | — | US | disclosed |
| US-20210317083-A1 | NOVEL HALO-(3-(PHENYLSULFONYL)PROP-1-ENYL)PYRIDINE DERIVATIVE AND USE THEREOF | CUREVERSE INCORPORATED (KR) | 2021-10-14 | — | — | US | disclosed |
| EP-3838896-A1 | NOVEL HALO-(3-(PHENYLSULFONYL)PROP-1-ENYL)PYRIDINE DERIVATIVE AND USE THEREOF | Korea Institute of Science and Technology (KR) | 2021-06-23 | — | — | EP | disclosed |
| CN-112930345-A | Novel halo- (3- (phenylsulfonyl) prop-1-ene) pyridine derivatives and uses thereof | 韩国科学技术研究院 | 2021-06-08 | — | — | CN | disclosed |
| WO-2020036474-A1 | NOVEL HALO-(3-(PHENYLSULFONYL)PROP-1-ENYL)PYRIDINE DERIVATIVE AND USE THEREOF | 한국과학기술연구원 | 2020-02-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317083-A1 | NOVEL HALO-(3-(PHENYLSULFONYL)PROP-1-ENYL)PYRIDINE DERIVATIVE AND USE THEREOF | KEAP1, NFE2L2, BACH1 | NPSR1 3057/4885GAA 2123/4885POLB 2663/4885 |
| US-12234207-B2 | Halo-(3-(phenylsulfonyl)prop-1-enyl)pyridine derivative and use thereof | KEAP1, NFE2L2, NQO1 | NPSR1 2856/4885GAA 2114/4885POLB 2502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.