SCHEMBL31248756

SCHEMBL31248756

Cc1cc2c(Br)cc(OS(=O)(=O)C(F)(F)F)cc2n(C)c1=O

nearest known ligand 0.34

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ L3MBTL1 Q9Y468 1/20 0.34
▸ BRPF1 P55201 4/20 0.34
▸ BRD1 O95696 2/20 0.34
▸ BRPF3 Q9ULD4 1/20 0.34
▸ THRB P10828 2/20 0.33
▸ EGFR P00533 1/20 0.32
▸ HDAC8 Q9BY41 1/20 0.31
▸ BRD4 O60885 1/20 0.31
▸ TSHR P16473 2/20 0.31
▸ LMNA P02545 1/20 0.31
▸ DRD2 P14416 2/20 0.31
▸ DRD1 P21728 2/20 0.31
▸ DRD4 P21917 2/20 0.31
▸ DRD5 P21918 2/20 0.31
▸ DRD3 P35462 2/20 0.31
▸ TTR P02766 1/20 0.31
▸ SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31248757 0.83 SMN1; SMN2 (0.37) MEN1KMT2AL3MBTL1BRPF1EGFR
SCHEMBL31248652 0.83 MEN1 (0.34) MEN1KMT2AL3MBTL1BRPF1EGFR
SCHEMBL26547632 0.81 CYP19A1 (0.43) MEN1KMT2AL3MBTL1BRPF1THRB
SCHEMBL26547726 0.77 KMT2A (0.34) MEN1KMT2AL3MBTL1BRPF1EGFR
SCHEMBL31248639 0.77 KMT2A (0.34) MEN1KMT2AL3MBTL1BRPF1EGFR
SCHEMBL31393691 0.76 EGFR (0.36) EGFRDRD2DRD4DRD3SMN1; SMN2
SCHEMBL31248637 0.76 BRPF1 (0.43) MEN1KMT2AL3MBTL1BRPF1EGFR
SCHEMBL31248926 0.75 BRPF1 (0.33) BRPF1BRD1BRPF3THRBHDAC8
SCHEMBL26547732 0.74 ACACB (0.38) MEN1KMT2AL3MBTL1BRPF1EGFR
SCHEMBL31248918 0.74 DRD2 (0.36) BRPF1BRD1BRPF3THRBDRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4720057-A2 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF Oncopia Therapeutics, Inc. D/B/A SK Life Science Labs (US) 2026-04-08 — — EP disclosed
US-20250114345-A1 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF ONCOPIA THERAPEUTICS, INC. D/B/A/ SK LIFE SCIENCE LABS 2025-04-10 — — US disclosed
WO-2025049976-A1 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF ONCOPIA THERAPEUTICS, INC. D/B/A SK LIFE SCIENCE LABS (US) 2025-03-06 — — WO disclosed
WO-2025049994-A1 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF ONCOPIA THERAPEUTICS, INC. D/B/A SK LIFE SCIENCE LABS (US) 2025-03-06 — — WO disclosed
WO-2024249888-A2 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF ONCOPIA THERAPEUTICS, INC. D/B/A SK LIFE SCIENCE LABS (US) 2024-12-05 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250114345-A1 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF EP300, CREBBP, HDAC1 MEN1 2485/4885KMT2A 689/4885L3MBTL1 2199/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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