Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13606472 | 0.84 | TSHR (0.49) | GPR35TSHRCTSDALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL28210415 | 0.83 | TSHR (0.47) | GPR35TSHRCTSDALDH1A1MEN1 | |
| SCHEMBL1206488 | 0.82 | CTSD (0.58) | GPR35CTSDALDH1A1GAAMEN1 | |
| SCHEMBL11823030 | 0.81 | GPR35 (0.47) | GPR35TSHRCTSDALDH1A1GAA | |
| SCHEMBL1784383 | 0.79 | TSHR (0.65) | TSHRALDH1A1GAAMEN1KMT2A | |
| SCHEMBL27966670 | 0.79 | GPR35 (0.46) | GPR35TSHRCTSDALDH1A1GAA | |
| SCHEMBL16951731 | 0.79 | TSHR (0.50) | GPR35TSHRCTSDALDH1A1MEN1 | |
| SCHEMBL6402 | 0.79 | TSHR (0.64) | GPR35TSHRCTSDALDH1A1GAA | |
| SCHEMBL29025719 | 0.79 | TSHR (0.50) | GPR35TSHRCTSDALDH1A1MEN1 | |
| SCHEMBL6903592 | 0.78 | ALDH1A1 (0.44) | GPR35TSHRCTSDALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3773577-B1 | TRICYCLIC ASK1 INHIBITORS | TERNS INC (US) | 2024-11-20 | — | — | EP | disclosed |