Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | TYMS | P04818 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6792974 | 0.85 | TSHR (0.51) | ALDH1A1GPR35PLAUTYMSTSHR | |
| SCHEMBL1206488 | 0.80 | CTSD (0.58) | ALDH1A1GPR35PLAUCTSDMEN1 | |
| SCHEMBL2870921 | 0.79 | TSHR (0.62) | ALDH1A1GPR35TSHRCTSDMEN1 | |
| SCHEMBL11823030 | 0.79 | GPR35 (0.47) | ALDH1A1GPR35PDE10APLAUTSHR | |
| SCHEMBL23909592 | 0.78 | TSHR (0.47) | ALDH1A1GPR35PDE10ATYMSTSHR | |
| SCHEMBL1784383 | 0.78 | TSHR (0.65) | ALDH1A1TSHRMEN1GAAKMT2A | |
| SCHEMBL27966670 | 0.78 | GPR35 (0.46) | ALDH1A1GPR35PLAUTSHRCTSD | |
| SCHEMBL12920010 | 0.78 | TSHR (0.51) | ALDH1A1GPR35TSHRCTSDMEN1 | |
| SCHEMBL31249012 | 0.78 | GPR35 (0.46) | ALDH1A1GPR35PLAUTSHRCTSD | |
| SCHEMBL187697 | 0.78 | ALDH1A1 (0.61) | ALDH1A1GPR35PDE10ATYMSTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002032856-A9 | INSECTICIDAL 1,8-NAPHTHALENEDICARBOXAMIDES | DU PONT (US) | 2004-04-08 | — | — | WO | disclosed |
| US-20040053786-A1 | Insecticidal 1,8-naphthalenedicarboxamides | E.I. DU PONT DE NEMOURS AND COMPANY | 2004-03-18 | — | — | US | disclosed |
| EP-1326827-A2 | INSECTICIDAL 1,8-NAPHTHALENEDICARBOXAMIDES | E. I. du Pont de Nemours and Company (US) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002032856-A2 | INSECTICIDAL 1,8-NAPHTHALENEDICARBOXAMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-04-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040053786-A1 | Insecticidal 1,8-naphthalenedicarboxamides | DDT, NIT2, ACHE | ALDH1A1 994/4885GPR35 3895/4885PDE10A 1472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.