Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 7/20 | 0.52 |
| ▸ | CTSK | P43235 | 6/20 | 0.52 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | KCNQ4 | P56696 | 2/20 | 0.41 |
| ▸ | KCNQ5 | Q9NR82 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.39 |
| ▸ | PTPRA | P18433 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20202782 | 0.89 | CTSS (0.54) | CTSSCTSKSCN9ACTSLCTSB | |
| SCHEMBL18239928 | 0.86 | CTSS (0.53) | CTSSCTSKSCN9ACTSLCTSB | |
| SCHEMBL20208717 | 0.86 | CTSS (0.53) | CTSSCTSKSCN9ACTSLCTSB | |
| SCHEMBL18239927 | 0.83 | CTSS (0.60) | CTSSCTSKSCN9ACTSLCTSB | |
| SCHEMBL29635621 | 0.81 | CTSS (0.51) | CTSSCTSKSCN9ACTSLCTSB | |
| SCHEMBL29635622 | 0.81 | CTSS (0.51) | CTSSCTSKSCN9ACTSLCTSB | |
| SCHEMBL29635623 | 0.81 | CTSS (0.51) | CTSSCTSKSCN9ACTSLCTSB | |
| SCHEMBL29780768 | 0.78 | CTSS (0.52) | CTSSCTSKSCN9ACTSLCTSB | |
| SCHEMBL24101175 | 0.76 | CTSS (0.52) | CTSSCTSKSCN9ACTSLCTSB | |
| SCHEMBL28576290 | 0.76 | LMNA (0.59) | CTSSCTSKSCN9ACTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250115637-A1 | COMPOUNDS CONTAINING DEUTERIUM | ONCOPEPTIDES INNOVATION AB (SE) | 2025-04-10 | — | — | US | disclosed |
| US-12152087-B2 | Deuterated melflufen compounds | ONCOPEPTIDES INNOVATION AB (SE) | 2024-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250115637-A1 | COMPOUNDS CONTAINING DEUTERIUM | DHX30, H1-10, REN | CTSS 1685/4885CTSK 1231/4885SCN9A 954/4885 |
| US-12152087-B2 | Deuterated melflufen compounds | MC2R, MTNR1A, DHX30 | CTSS 3230/4885CTSK 2434/4885SCN9A 1345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.