Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | GPR6 | P46095 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | MLKL | Q8NB16 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL31255582 | 0.96 | PKM (0.45) | PKMKDM4EALDH1A1SOS1NR3C1 | |
| Trifluoroacetic Acid SCHEMBL31255689 | 0.92 | SOS1 (0.46) | PKMKDM4EALDH1A1SOS1NR3C1 | |
| Trifluoroacetic Acid SCHEMBL31696980 | 0.90 | PKM (0.46) | PKMKDM4EALDH1A1SOS1NR3C1 | |
| SCHEMBL30278909 | 0.90 | NR3C1 (0.41) | KDM4EALDH1A1SOS1NR3C1PGR | |
| Trifluoroacetic Acid SCHEMBL31255479 | 0.90 | PKM (0.57) | PKMKDM4EALDH1A1SOS1NR3C1 | |
| SCHEMBL27137025 | 0.88 | RBP4 (0.38) | ALDH1A1SOS1NR3C1PGRSLC6A4 | |
| Trifluoroacetic Acid SCHEMBL31255584 | 0.86 | SOS1 (0.42) | PKMKDM4EALDH1A1SOS1NR3C1 | |
| SCHEMBL31586935 | 0.86 | NR3C1 (0.41) | KDM4EALDH1A1SOS1NR3C1PGR | |
| SCHEMBL31586917 | 0.86 | NR3C1 (0.42) | KDM4EALDH1A1SOS1NR3C1PGR | |
| SCHEMBL31255602 | 0.86 | L3MBTL3 (0.44) | KDM4EALDH1A1NR3C1PGRSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720044-A1 | AROMATIC AMIDES AND CONJUGATES THEREOF AS BINDERS TO TEAD | Beactica Therapeutics AB (SE) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024240840-A1 | AROMATIC AMIDES AND CONJUGATES THEREOF AS BINDERS TO TEAD | BEACTICA THERAPEUTICS AB (SE) | 2024-11-28 | — | — | WO | disclosed |