Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29469063 | 1.00 | ENPP2 (0.41) | ENPP2ALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL6375203 | 0.87 | PDK2 (0.40) | ENPP2ALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL29085598 | 0.87 | LMNA (0.41) | ENPP2ALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL13863275 | 0.86 | SMN1; SMN2 (0.43) | ENPP2ALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL132959 | 0.81 | ALDH1A1 (0.59) | ALDH1A1KDM4ESMN1; SMN2ALOX15POLB | |
| SCHEMBL29446522 | 0.81 | ALDH1A1 (0.59) | ALDH1A1KDM4ESMN1; SMN2ALOX15POLB | |
| SCHEMBL3784961 | 0.80 | THRB (0.45) | ENPP2ALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL54119 | 0.79 | KDM4E (0.52) | ENPP2ALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL29468958 | 0.79 | KDM4E (0.52) | ENPP2ALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL1794820 | 0.79 | ENPP2 (0.40) | ENPP2ALDH1A1KDM4ESMN1; SMN2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 689 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12116698-B1 | Protein surface recognition via chemically enhanced phage display | THE TRUSTEES OF BOSTON COLLEGE (MA) | 2024-10-15 | — | — | US | claimed |
| CN-114939172-B | Preparation method of plant polyphenol modified antibiotic nano particles, product and application thereof | 温州医科大学附属第一医院 | 2024-01-26 | — | — | CN | claimed |
| CN-117126185-A | Difluoro boron beta-diketonate complex fluorescent probe and preparation method and application thereof | 西北工业大学深圳研究院 | 2023-11-28 | — | — | CN | claimed |
| CN-117126397-A | Synthesis method and application of protein-binding type precise polyethylene glycol | 中国科学技术大学 | 2023-11-28 | — | — | CN | claimed |
| US-11788080-B2 | Modified cleavases, uses thereof and related kits | Encodia, Inc. (US) | 2023-10-17 | — | — | US | claimed |
| US-20230257727-A1 | MODIFIED CLEAVASES, USES THEREOF AND RELATED KITS | Encodia, Inc. (US) | 2023-08-17 | — | — | US | claimed |
| US-11655468-B2 | Methods and compositions of chemically modified phage libraries | THE TRUSTEES OF BOSTON COLLEGE (MA) | 2023-05-23 | — | — | US | claimed |
| CN-115282287-A | Protein nano delivery system and construction method and application thereof | 国科温州研究院(温州生物材料与工程研究所) | 2022-11-04 | — | — | CN | claimed |
| US-11427814-B2 | Modified cleavases, uses thereof and related kits | Encodia, Inc. (US) | 2022-08-30 | — | — | US | claimed |
| CN-114939172-A | Preparation method of plant polyphenol modified antibiotic nanoparticles, product and application thereof | 温州医科大学附属第一医院 | 2022-08-26 | — | — | CN | claimed |
| CN-112485442-A | Small molecule target screening method based on chemical proteomics and application thereof | 中国药科大学 | 2021-03-12 | — | — | CN | claimed |
| WO-2020198264-A1 | MODIFIED CLEAVASES, USES THEREOF AND RELATED KITS | Encodia, Inc. (US) | 2020-10-01 | — | — | WO | claimed |
| CN-111171721-A | Ceramizable ablation-resistant coating and preparation method thereof | 西安近代化学研究所 | 2020-05-19 | — | — | CN | claimed |
| US-8361484-B2 | Polymer systems for lung volume reduction therapy | AERIS THERAPEUTICS, INC. (US) | 2013-01-29 | — | — | US | claimed |
| US-8119680-B2 | α-Haloketone derivatives of imidazolyl-substituted aromatic compounds and compounds prepared therefrom | NEUROGENETIC PHARMACEUTICALS, INC. (US) | 2012-02-21 | — | — | US | claimed |
| US-20100331551-A1 | ALPHA-HALOKETONE DERIVATIVES OF IMIDAZOLYL-SUBSTITUTED AROMATIC COMPOUNDS AND COMPOUNDS PREPARED THEREFROM | NEUROGENETIC PHARMACEUTICALS, INC | 2010-12-30 | — | — | US | claimed |
| US-7825104-B2 | Methods and compositions for treating fungal infections | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2010-11-02 | — | — | US | claimed |
| US-20100040538-A1 | Polymer Systems for Lung Volume Reduction Therapy | CANADIAN IMPERIAL BANK OF COMMERCE (CA) | 2010-02-18 | — | — | US | claimed |
| EP-2059227-A2 | POLYMER SYSTEMS FOR LUNG VOLUME REDUCTION THERAPY | Aeris Therapeutics, Inc. (US) | 2009-05-20 | — | — | EP | claimed |
| WO-2008039827-A2 | POLYMER SYSTEMS FOR LUNG VOLUME REDUCTION THERAPY | AERIS THERAPEUTICS, INC. (US) | 2008-04-03 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12116698-B1 | Protein surface recognition via chemically enhanced phage display | APBA1, CLTB, APMAP | ENPP2 1704/4885ALDH1A1 3598/4885KDM4E 3470/4885 |
| US-20100040538-A1 | Polymer Systems for Lung Volume Reduction Therapy | GFER, MUC1, CTH | ENPP2 854/4885ALDH1A1 1749/4885KDM4E 1589/4885 |
| US-20100331551-A1 | ALPHA-HALOKETONE DERIVATIVES OF IMIDAZOLYL-SUBSTITUTED AROMATIC COMPOUNDS AND COMPOUNDS PREPARED THEREFROM | HYPK, APP, NEFM | ENPP2 4450/4885ALDH1A1 2013/4885KDM4E 3526/4885 |
| US-11655468-B2 | Methods and compositions of chemically modified phage libraries | CLTB, PTMS, RNPEP | ENPP2 261/4885ALDH1A1 2081/4885KDM4E 3148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.