Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.37 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL791333 | 0.79 | GAA (0.57) | KDM4EPOLB | |
| SCHEMBL29402736 | 0.79 | TSHR (0.59) | ALDH1A1CFTRHSD17B10LMNATSHR | |
| SCHEMBL29469069 | 0.79 | GAA (0.57) | KDM4EPOLB | |
| SCHEMBL129359 | 0.79 | TSHR (0.59) | ALDH1A1CFTRHSD17B10LMNATSHR | |
| SCHEMBL692347 | 0.77 | ALDH1A1 (0.66) | ALDH1A1CFTRHSD17B10KDM4EMAPK1 | |
| SCHEMBL17545031 | 0.77 | LMNA (0.62) | ALDH1A1HSD17B10LMNATSHRCA1 | |
| SCHEMBL31255734 | 0.77 | GAA (0.37) | CTSDALDH1A1ENPP2LMNATSHR | |
| SCHEMBL7126868 | 0.77 | HPGD (0.56) | PTGS2ALDH1A1LMNAKMT2AKDM4E | |
| SCHEMBL31255732 | 0.77 | GAA (0.37) | CTSDALDH1A1ENPP2LMNATSHR | |
| SCHEMBL27314785 | 0.77 | TSHR (0.57) | ALDH1A1CFTRHSD17B10LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979353-A2 | FUSED HETEROBICYCLIC KINASE INHIBITORS | OSI Pharmaceuticals, Inc. (US) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007084667-A2 | FUSED HETEROBICYCLIC KINASE INHIBITORS | OSI PHARMACEUTICAL, INC. (US) | 2007-07-26 | — | — | WO | disclosed |