Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 3/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.40 |
| ▸ | AOC2 | O75106 | 5/20 | 0.39 |
| ▸ | MAOA | P21397 | 5/20 | 0.39 |
| ▸ | MAOB | P27338 | 5/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30098429 | 0.79 | AOC2 (0.39) | HPGDTSHRPARP1NISCHGABRA1 | |
| SCHEMBL5023943 | 0.79 | HPGD (0.39) | HPGDTSHRPARP1NISCHGABRA1 | |
| SCHEMBL860446 | 0.78 | HPGD (0.59) | HPGDTSHRNISCHAOC2MAOA | |
| SCHEMBL29974170 | 0.78 | HPGD (0.59) | HPGDTSHRNISCHAOC2MAOA | |
| SCHEMBL31646098 | 0.77 | AOC2 (0.40) | HPGDTSHRNISCHGABRA1GABRB2 | |
| SCHEMBL28147404 | 0.74 | MAOA (0.41) | HPGDTSHRNISCHGABRA1GABRB2 | |
| SCHEMBL7313976 | 0.74 | AOC2 (0.41) | HPGDTSHRNISCHGABRA1GABRB2 | |
| SCHEMBL5015240 | 0.74 | MMP3 (0.42) | HPGDTSHRNISCHGABRA1GABRB2 | |
| SCHEMBL8504530 | 0.73 | CHRM2 (0.41) | HPGDTSHRNISCHGABRA1GABRB2 | |
| Hydrochloric Acid SCHEMBL10598707 | 0.73 | AOC2 (0.43) | HPGDTSHRNISCHGABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4698529-A1 | BLOOD BRAIN BARRIER PENETRATING SELECTIVE INHIBITORS OF ROCK2 PROTEIN KINASES AND USES THEREOF | Genosco Inc. (US) | 2026-02-25 | — | — | EP | disclosed |
| WO-2024220173-A1 | BLOOD BRAIN BARRIER PENETRATING SELECTIVE INHIBITORS OF ROCK2 PROTEIN KINASES AND USES THEREOF | Genosco Inc. (US) | 2024-10-24 | — | — | WO | disclosed |