Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15271666 | 0.92 | TP53 (0.36) | MEN1USP2TP53POLBMAPT | |
| SCHEMBL15271359 | 0.86 | TP53 (0.37) | MEN1USP2TP53POLBMAPT | |
| SCHEMBL20108 | 0.72 | ALOX15 (0.43) | TP53MAPTHPGDALOX15MAPK1 | |
| SCHEMBL30442982 | 0.72 | ALOX15 (0.43) | TP53MAPTHPGDALOX15MAPK1 | |
| Lithium SCHEMBL31258223 | 0.70 | ALOX15 (0.42) | TP53HPGDALOX15MAPK1 | |
| SCHEMBL1833452 | 0.69 | MCL1 (0.46) | MEN1USP2TP53POLBMAPT | |
| SCHEMBL13206417 | 0.67 | ALOX15 (0.40) | TP53HPGDALOX15MAPK1MCL1 | |
| SCHEMBL1120183 | 0.67 | HPGD (0.34) | TP53HPGDALOX15MAPK1 | |
| SCHEMBL1120133 | 0.65 | MCL1 (0.42) | MEN1USP2TP53POLBMAPT | |
| SCHEMBL15375205 | 0.62 | CA2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111354974-B | High voltage stable copolymers for forming polymer electrolytes for lithium or sodium batteries | 罗伯特·博世有限公司 | 2024-11-26 | — | — | CN | disclosed |