Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 16/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22632422 | 1.00 | RORC (0.35) | RORCNAMPTDGAT1ADAMTS4MAPK14 | |
| SCHEMBL22638209 | 0.90 | PDE4A (0.35) | — | |
| SCHEMBL22632392 | 0.88 | PDE4A (0.34) | RORCMAPK14 | |
| SCHEMBL31690725 | 0.88 | PDE4A (0.34) | RORCMAPK14 | |
| SCHEMBL29414839 | 0.87 | ALDH1A1 (0.41) | — | |
| SCHEMBL22632537 | 0.83 | PTPN11 (0.32) | — | |
| SCHEMBL22632665 | 0.83 | ALK (0.35) | — | |
| SCHEMBL22632891 | 0.82 | L3MBTL1 (0.34) | — | |
| SCHEMBL22632745 | 0.81 | L3MBTL1 (0.32) | — | |
| SCHEMBL22632642 | 0.80 | PTGS2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3965884-B1 | MODULATORS OF THR-BETA WITH A DIOXO-1,2,4-TRIAZYL HEAD GROUP | ALIGOS THERAPEUTICS INC (US) | 2025-01-15 | — | — | EP | disclosed |