Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.52 |
| ▸ | ALDH5A1 | P51649 | 3/20 | 0.47 |
| ▸ | ABAT | P80404 | 3/20 | 0.47 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 2/20 | 0.42 |
| ▸ | ERN1 | O75460 | 2/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL430962 | 1.00 | KDM4E (0.64) | KDM4EPTGS2RAB9AALDH1A1AOX1 | |
| SCHEMBL151496 | 0.82 | KDM4E (0.64) | KDM4EPTGS2RAB9AALDH1A1AOX1 | |
| SCHEMBL6902242 | 0.78 | ALDH1A1 (0.46) | KDM4EPTGS2RAB9AALDH1A1AOX1 | |
| Protocatechualdehyde SCHEMBL9512877 | 0.78 | KDM4E (1.00) | KDM4EPTGS2RAB9AALDH1A1AOX1 | |
| Protocatechualdehyde SCHEMBL29349539 | 0.78 | KDM4E (1.00) | KDM4EPTGS2RAB9AALDH1A1AOX1 | |
| Protocatechualdehyde SCHEMBL36350 | 0.78 | KDM4E (1.00) | KDM4EPTGS2RAB9AALDH1A1AOX1 | |
| Protocatechualdehyde SCHEMBL28071658 | 0.77 | KDM4E (0.86) | KDM4EPTGS2RAB9AALDH1A1AOX1 | |
| Protocatechualdehyde SCHEMBL27876787 | 0.76 | KDM4E (0.95) | KDM4EPTGS2RAB9AALDH1A1AOX1 | |
| Protocatechualdehyde SCHEMBL27748932 | 0.76 | KDM4E (0.95) | KDM4EPTGS2RAB9AALDH1A1AOX1 | |
| Protocatechualdehyde SCHEMBL4072910 | 0.76 | KDM4E (0.95) | KDM4EPTGS2RAB9AALDH1A1AOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4716685-A1 | IMIDAZO[4,5-C]PYRIDINE COMPOUNDS FOR THE TREATMENT OF CANCER | F. Hoffmann-La Roche AG (CH) | 2026-04-01 | — | — | EP | disclosed |
| WO-2024240726-A1 | IMIDAZO[4,5-C]PYRIDINE COMPOUNDS FOR THE TREATMENT OF CANCER | F. HOFFMANN-LA ROCHE AG (CH) | 2024-11-28 | — | — | WO | disclosed |