SCHEMBL31265899

SCHEMBL31265899

Nc1cccc(-c2ccc3c(c2)Cc2cc(-c4cccc(N)c4)ccc2-3)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP2 O95551 3/20 0.64
▸ LMNA P02545 2/20 0.55
▸ MAPT P10636 2/20 0.55
▸ RAB9A P51151 2/20 0.55
▸ KDM4E B2RXH2 1/20 0.55
▸ NPC1 O15118 1/20 0.55
▸ ALDH1A1 P00352 1/20 0.55
▸ HPGD P15428 1/20 0.55
▸ SMN1; SMN2 Q16637 1/20 0.55
▸ MAOA P21397 1/20 0.54
▸ PRF1 P14222 1/20 0.48
▸ MAP4K4 O95819 3/20 0.47
▸ CYP3A4 P08684 2/20 0.46
▸ CYP17A1 P05093 1/20 0.46
▸ CYP19A1 P11511 1/20 0.46
▸ CYP11B1 P15538 1/20 0.46
▸ CYP11B2 P19099 1/20 0.46
▸ CA12 O43570 1/20 0.46
▸ CA1 P00915 1/20 0.46
▸ CA2 P00918 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19847534 0.93 KDM4E (0.68) TDP2LMNAMAPTRAB9AKDM4E
SCHEMBL30469252 0.93 KDM4E (0.68) TDP2LMNAMAPTRAB9AKDM4E
SCHEMBL19847551 0.85 LMNA (0.67) TDP2LMNAMAPTRAB9AKDM4E
SCHEMBL19673668 0.82 RAB9A (0.62) TDP2LMNAMAPTRAB9AKDM4E
SCHEMBL12379605 0.82 MAOA (0.56) TDP2LMNAMAPTKDM4EALDH1A1
SCHEMBL18010827 0.79 TDP2 (1.00) TDP2
SCHEMBL1482920 0.79 TDP2 (0.61) TDP2LMNAMAPTRAB9AKDM4E
SCHEMBL3136254 0.79 TDP2 (0.61) TDP2LMNAMAPTRAB9AKDM4E
SCHEMBL29569358 0.79 TDP2 (0.61) TDP2LMNAMAPTRAB9AKDM4E
SCHEMBL311194 0.78 MAOA (0.84) TDP2LMNAMAPTKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119061512-B High-heat-resistance meta-aramid fibrid and preparation method and application thereof 泰和新材集团股份有限公司 2025-01-21 — — CN claimed
CN-119061512-A High-heat-resistance meta-aramid fibrid and preparation method and application thereof 泰和新材集团股份有限公司 2024-12-03 — — CN claimed
CN-119061512-B High-heat-resistance meta-aramid fibrid and preparation method and application thereof 泰和新材集团股份有限公司 2025-01-21 — — CN disclosed
CN-119061512-A High-heat-resistance meta-aramid fibrid and preparation method and application thereof 泰和新材集团股份有限公司 2024-12-03 — — CN disclosed
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