Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 4/20 | 0.62 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.62 |
| ▸ | PRKACA | P17612 | 3/20 | 0.62 |
| ▸ | GSK3B | P49841 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.52 |
| ▸ | OGFRL1 | Q5TC84 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28236159 | 0.88 | CYP11B2 (0.63) | RPS6KB1ROCK1PRKACAGSK3BTP53 | |
| SCHEMBL26017426 | 0.83 | SMN1; SMN2 (0.52) | RPS6KB1ROCK1PRKACAGSK3BALDH1A1 | |
| SCHEMBL26017367 | 0.81 | LMNA (0.53) | RPS6KB1ROCK1PRKACAGSK3BKDM4E | |
| SCHEMBL31267525 | 0.81 | ALDH1A1 (0.60) | RPS6KB1ROCK1PRKACAGSK3BKDM4E | |
| SCHEMBL15315971 | 0.80 | HDAC1 (0.60) | RPS6KB1ROCK1PRKACAGSK3BTP53 | |
| SCHEMBL21311255 | 0.79 | OPRM1 (0.59) | RPS6KB1ROCK1PRKACAGSK3BKDM4E | |
| SCHEMBL2929873 | 0.77 | RPS6KB1 (0.58) | RPS6KB1ROCK1PRKACAGSK3BTP53 | |
| SCHEMBL6405625 | 0.76 | RPS6KB1 (1.00) | RPS6KB1ROCK1PRKACAGSK3B | |
| SCHEMBL5516174 | 0.76 | PDE6D (0.49) | RPS6KB1ROCK1PRKACAGSK3BALDH1A1 | |
| SCHEMBL27672884 | 0.76 | L3MBTL1 (0.65) | RPS6KB1ROCK1PRKACAGSK3BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119306668-A | Benzimidazole compound, and preparation method and application thereof | 中国医学科学院药物研究所 | 2025-01-14 | — | — | CN | disclosed |