Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 4/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31269269 | 0.88 | DRD2 (0.33) | DRD2HRH4PIK3CDESR1ESR2 | |
| SCHEMBL30984048 | 0.88 | PDE2A (0.38) | DRD2HRH4KDM4EALDH1A1CNR1 | |
| SCHEMBL30983856 | 0.87 | CNR1 (0.41) | PIK3CDCNR1 | |
| SCHEMBL30983550 | 0.86 | PDK2 (0.37) | DRD2HRH4KDM4EPIK3CDCNR1 | |
| SCHEMBL31269351 | 0.86 | PIK3CD (0.35) | HRH4PIK3CDCNR1KCNH2 | |
| SCHEMBL31269005 | 0.85 | PDE2A (0.35) | HRH4PIK3CDCNR1KCNH2 | |
| SCHEMBL31268792 | 0.85 | HRH4 (0.35) | HRH4PIK3CDCNR1KCNH2 | |
| SCHEMBL31269116 | 0.85 | ESR1 (0.38) | DRD2HRH4KDM4EESR1ESR2 | |
| SCHEMBL31269218 | 0.85 | THRB (0.38) | HRH4THRBKDM4EALDH1A1PIK3CD | |
| SCHEMBL30983885 | 0.84 | CNR1 (0.33) | HRH4PIK3CDCNR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4689155-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | Astrazeneca AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024201368-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | ASTRAZENECA AB (SE) | 2024-10-03 | — | — | WO | disclosed |