Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 11/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 11/20 | 0.40 |
| ▸ | CHRNB1 | P11230 | 10/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 10/20 | 0.40 |
| ▸ | CHRNB3 | Q05901 | 10/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31269171 | 0.86 | DRD2 (0.37) | — | |
| SCHEMBL31269436 | 0.86 | CHRNA3 (0.36) | CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL31269323 | 0.86 | HRH4 (0.40) | — | |
| SCHEMBL31269245 | 0.85 | PIK3CD (0.35) | — | |
| SCHEMBL31268969 | 0.85 | PIK3CD (0.37) | — | |
| SCHEMBL31269192 | 0.84 | PIK3CD (0.37) | — | |
| SCHEMBL31268820 | 0.83 | PIK3CD (0.33) | — | |
| SCHEMBL31269018 | 0.83 | PIK3CD (0.33) | — | |
| SCHEMBL31269378 | 0.83 | PIK3CD (0.34) | — | |
| SCHEMBL31268797 | 0.83 | TLR7 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4689155-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | Astrazeneca AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024201368-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | ASTRAZENECA AB (SE) | 2024-10-03 | — | — | WO | disclosed |