Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31145 | 0.83 | KDM4E (0.36) | KDM4EMAPK1ALDH1A1HIF1AHSD17B10 | |
| SCHEMBL15043600 | 0.81 | KDM4E (0.49) | KDM4EMAPK1ALDH1A1PKMHSD17B10 | |
| SCHEMBL31212 | 0.78 | KDM4E (0.34) | KDM4EMAPK1ALDH1A1KMT2AMEN1 | |
| SCHEMBL11941712 | 0.71 | ALDH1A1 (0.55) | KDM4EMAPK1ALDH1A1PKMHSD17B10 | |
| SCHEMBL31722261 | 0.70 | PTGS1 (0.50) | KDM4EMAPK1ALDH1A1HSD17B10NPSR1 | |
| SCHEMBL9947532 | 0.67 | MAPK1 (0.57) | KDM4EMAPK1ALDH1A1PKMHSD17B10 | |
| SCHEMBL7802853 | 0.67 | MAPK1 (0.53) | KDM4EMAPK1ALDH1A1PKMHSD17B10 | |
| SCHEMBL7806227 | 0.67 | MAPK1 (0.53) | KDM4EMAPK1ALDH1A1PKMHSD17B10 | |
| SCHEMBL10031686 | 0.67 | MAPK1 (1.00) | KDM4EMAPK1ALDH1A1HSD17B10POLB | |
| SCHEMBL31141366 | 0.67 | MAPK1 (1.00) | KDM4EMAPK1ALDH1A1HSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8816062-B2 | Maleimide-furanyl compounds that can be used in a general method for preparing maleimide-oligonucleotide derivatives | UNIVERSITAT DE BARCELONA (ES) | 2014-08-26 | — | — | US | disclosed |
| US-20130158248-A1 | MALEIMIDE-FURANYL COMPOUNDS THAT CAN BE USED IN A GENERAL METHOD FOR PREPARING MALEIMIDE-OLIGONUCLEOTIDE DERIVATIVES | UNIVERSITAT DE BARCELONA (ES) | 2013-06-20 | — | — | US | disclosed |
| WO-2012025646-A1 | MALEIMIDE‑FURANYL COMPOUNDS THAT CAN BE USED IN A GENERAL METHOD FOR PREPARING MALEIMIDE‑OLIGONUCLEOTIDE DERIVATIVES | UNIVERSITAT DE BARCELONA (ES) | 2012-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130158248-A1 | MALEIMIDE-FURANYL COMPOUNDS THAT CAN BE USED IN A GENERAL METHOD FOR PREPARING MALEIMIDE-OLIGONUCLEOTIDE DERIVATIVES | NSUN2, POLL, NT5C3B | KDM4E 729/4885MAPK1 4269/4885ALDH1A1 4111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.