Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PTPRC | P08575 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.30 |
| ▸ | S100A4 | P26447 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4011227 | 0.71 | RXRA (0.37) | — | |
| SCHEMBL3906602 | 0.70 | ALDH1A1 (0.50) | ALDH1A1MAPK1PTPRC | |
| SCHEMBL2732723 | 0.69 | — | — | |
| SCHEMBL20955794 | 0.67 | ALDH1A1 (0.58) | ALDH1A1MAPK1PTPN1HSP90AA1 | |
| SCHEMBL3748766 | 0.67 | ALDH1A1 (0.58) | ALDH1A1MAPK1PTPN1HSP90AA1 | |
| SCHEMBL28685012 | 0.67 | ESR2 (0.44) | ALDH1A1 | |
| Methane SCHEMBL27616972 | 0.67 | ALDH1A1 (0.33) | ALDH1A1 | |
| Methane SCHEMBL509019 | 0.67 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL28542905 | 0.65 | S100A4 (0.48) | ALDH1A1MAPK1PTPRCHSP90AA1TLR9 | |
| Ethane SCHEMBL6257492 | 0.64 | SMN1; SMN2 (0.32) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | disclosed |