SCHEMBL31284349

SCHEMBL31284349

O=C(O)[C@H](Cc1ccc(O)c(O)c1)NS

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM6B O15054 1/20 0.65
▸ KDM4E B2RXH2 6/20 0.58
▸ HSD17B10 Q99714 6/20 0.58
▸ TDP1 Q9NUW8 5/20 0.58
▸ ALOX15 P16050 4/20 0.58
▸ HIF1A Q16665 4/20 0.58
▸ RECQL P46063 4/20 0.58
▸ USP2 O75604 2/20 0.58
▸ ADORA3 P0DMS8 2/20 0.58
▸ HTR2A P28223 2/20 0.58
▸ PTGS2 P35354 2/20 0.58
▸ LCK P06239 2/20 0.58
▸ EGFR P00533 1/20 0.58
▸ FYN P06241 1/20 0.58
▸ PTGS1 P23219 1/20 0.58
▸ SLC7A5 Q01650 1/20 0.58
▸ MME P08473 1/20 0.55
▸ ACE P12821 1/20 0.55
▸ PLA2G1B P04054 1/20 0.55
▸ CA1 P00915 4/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30724831 0.86 KDM6B (0.64) KDM6BKDM4EHSD17B10TDP1ALOX15
SCHEMBL24489505 0.86 KDM6B (0.47) KDM6BKDM4EHSD17B10TDP1ALOX15
SCHEMBL5063603 0.85 KDM6B (0.62) KDM6BKDM4EHSD17B10TDP1ALOX15
SCHEMBL29669984 0.85 KDM6B (0.62) KDM6BKDM4EHSD17B10TDP1ALOX15
SCHEMBL29429645 0.85 KDM6B (0.62) KDM6BKDM4EHSD17B10TDP1ALOX15
Hydrochloric Acid SCHEMBL10782448 0.84 KDM6B (0.61) KDM6BKDM4EHSD17B10TDP1ALOX15
SCHEMBL18800390 0.83 KDM6B (0.60) KDM6BKDM4EHSD17B10TDP1ALOX15
SCHEMBL2283369 0.83 KDM6B (0.60) KDM6BKDM4EHSD17B10TDP1ALOX15
SCHEMBL22473033 0.83 CA2 (0.61) KDM6BKDM4EHSD17B10TDP1ALOX15
SCHEMBL3736877 0.83 KDM6B (0.60) KDM6BKDM4EHSD17B10TDP1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4746847-A2 COMPOSITION & METHODS FOR REGULATING MELANOGENESIS Sytheon Ltd. (US) 2026-05-27 — — EP disclosed
WO-2025019573-A2 COMPOSITION & METHODS FOR REGULATING MELANOGENESIS SYTHEON LTD. (US) 2025-01-23 — — WO disclosed
US-12171852-B1 Composition and methods for regulating melanogenesis SYTHEON LTD (US) 2024-12-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12171852-B1 Composition and methods for regulating melanogenesis TYR, MITF, MC1R KDM6B 80/4885KDM4E 241/4885HSD17B10 1364/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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