SCHEMBL3128471

SCHEMBL3128471

Cc1ccccc1N(c1ccc(C2C=CC(c3ccccc3)(N(c3ccccc3C)c3ccccc3C)C=C2)cc1)c1ccccc1C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL223877 0.85 HSD11B1 (0.31)
SCHEMBL4213708 0.80 ALDH1A1 (0.35)
SCHEMBL19125480 0.76 KDM4E (0.32)
SCHEMBL2348824 0.75
SCHEMBL8862830 0.75
SCHEMBL1042269 0.74 SIGMAR1 (0.32)
SCHEMBL9170581 0.73 CYP1A2 (0.32)
SCHEMBL253618 0.73 CNR2 (0.32)
SCHEMBL223517 0.72 CNR2 (0.38)
SCHEMBL223560 0.71 HDAC6 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7642029-B2 Imaging member XEROX CORPORATION (US) 2010-01-05 US claimed
US-20070172749-A1 Imaging member XEROX CORPORATION 2007-07-26 US claimed
US-20070099101-A1 Imaging member XEROX CORPORATION 2007-05-03 US claimed
US-7829252-B2 Imaging member XEROX CORPORATION (US) 2010-11-09 US disclosed
US-7642029-B2 Imaging member XEROX CORPORATION (US) 2010-01-05 US disclosed
US-7527903-B2 Imaging member XEROX CORPORATION (US) 2009-05-05 US disclosed
US-20070172749-A1 Imaging member XEROX CORPORATION 2007-07-26 US disclosed
US-20070099101-A1 Imaging member XEROX CORPORATION 2007-05-03 US disclosed
US-20070054208-A1 Imaging member XEROX CORPORATION 2007-03-08 US disclosed