Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3122081 | 0.84 | GAA (0.47) | MMP8ALOX15HSD17B10KMT2AGAA | |
| SCHEMBL3122032 | 0.77 | DPP4 (0.35) | HSD17B10KMT2ASMN1; SMN2TSHR | |
| SCHEMBL964201 | 0.73 | CYP2C9 (0.60) | HSD17B10KMT2AGAAALDH1A1MEN1 | |
| SCHEMBL3130509 | 0.73 | ALDH1A1 (0.44) | MMP8ALOX15HSD17B10KMT2AGAA | |
| SCHEMBL3121591 | 0.72 | MMP9 (0.39) | MMP8KMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL3130605 | 0.71 | SMN1; SMN2 (0.38) | HSD17B10KMT2AGAAALDH1A1MEN1 | |
| SCHEMBL3757565 | 0.71 | SMN1; SMN2 (0.48) | HSD17B10KMT2AGAAALDH1A1MEN1 | |
| SCHEMBL3122088 | 0.71 | FKBP1A (0.51) | ALDH1A1HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL3118094 | 0.71 | KCNA5 (0.38) | KMT2AGAAALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL3129274 | 0.69 | LMNA (0.49) | ALDH1A1HPGDSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | claimed |
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | disclosed |