Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 10/20 | 0.39 |
| ▸ | RET | P07949 | 2/20 | 0.35 |
| ▸ | PARP1 | P09874 | 3/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | ATXN2 | Q99700 | 1/20 | 0.33 |
| ▸ | MERTK | Q12866 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31293965 | 0.81 | SPR (0.39) | SPRRETPARP1PIK3CAMTOR | |
| SCHEMBL31293865 | 0.79 | VNN1 (0.37) | SPR | |
| SCHEMBL31293924 | 0.78 | EPHX2 (0.41) | — | |
| SCHEMBL31293617 | 0.78 | SPR (0.34) | SPR | |
| SCHEMBL31293519 | 0.76 | RAB9A (0.46) | — | |
| SCHEMBL31293851 | 0.75 | SCN10A (0.35) | ENPP2ATXN2 | |
| SCHEMBL31293678 | 0.75 | ADORA3 (0.33) | ADORA2A | |
| SCHEMBL31293980 | 0.74 | SPR (0.43) | SPR | |
| SCHEMBL31293858 | 0.74 | KMT2A (0.43) | — | |
| SCHEMBL31293875 | 0.74 | EPHX2 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4724439-A1 | HETEROARYL DERIVATIVES AS DDRS INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2026-04-15 | — | — | EP | disclosed |
| WO-2024251855-A1 | HETEROARYL DERIVATIVES AS DDRS INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2024-12-12 | — | — | WO | disclosed |