SCHEMBL31293983

SCHEMBL31293983

O=C(c1cnn2ccsc12)N1CC2(CC(N(C(=O)O)c3cc(C(F)(F)F)ncn3)C2)C1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SPR P35270 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31293812 0.83 SPR (0.30) SPR
SCHEMBL31293432 0.83 MGLL (0.32) SPR
SCHEMBL31293449 0.81 SPR (0.32) SPR
SCHEMBL31293471 0.81
SCHEMBL31293822 0.80 ABHD6 (0.34) SPR
SCHEMBL31293865 0.73 VNN1 (0.37) SPR
SCHEMBL31293617 0.73 SPR (0.34) SPR
SCHEMBL31293739 0.72 SPR (0.31) SPR
SCHEMBL31293751 0.70 POLB (0.34)
SCHEMBL31293980 0.69 SPR (0.43) SPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724439-A1 HETEROARYL DERIVATIVES AS DDRS INHIBITORS Chiesi Farmaceutici S.p.A. (IT) 2026-04-15 EP claimed
WO-2024251855-A1 HETEROARYL DERIVATIVES AS DDRS INHIBITORS CHIESI FARMACEUTICI S.P.A. (IT) 2024-12-12 WO claimed
EP-4724439-A1 HETEROARYL DERIVATIVES AS DDRS INHIBITORS Chiesi Farmaceutici S.p.A. (IT) 2026-04-15 EP disclosed
WO-2024251855-A1 HETEROARYL DERIVATIVES AS DDRS INHIBITORS CHIESI FARMACEUTICI S.P.A. (IT) 2024-12-12 WO disclosed