SCHEMBL31294874

SCHEMBL31294874

CN1C(=O)C(C)(F)c2c1cccc2C(C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.35
KDM4E B2RXH2 2/20 0.35
LMNA P02545 2/20 0.35
MAPT P10636 2/20 0.35
HTT P42858 2/20 0.35
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.35
CACNA1B Q00975 1/20 0.35
APBA1 Q02410 1/20 0.35
HCRTR1 O43613 1/20 0.33
CA2 P00918 1/20 0.33
KMT2A Q03164 2/20 0.33
MEN1 O00255 1/20 0.33
RBP4 P02753 2/20 0.31
TSHR P16473 1/20 0.31
RAD52 P43351 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.30
AR P10275 1/20 0.30
GABRA1 P14867 1/20 0.30
GABRB2 P47870 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31294885 0.77 RECQL (0.43) KDM4ELMNAMAPTHTTALDH1A1
SCHEMBL31294858 0.70 MAPT (0.53) KDM4ELMNAMAPTHTTALDH1A1
SCHEMBL19704112 0.65 MGLL (0.39) KDM4ELMNAMAPTHTTALDH1A1
SCHEMBL30082327 0.65 MGLL (0.39) KDM4ELMNAMAPTHTTALDH1A1
SCHEMBL26922415 0.64 JAK2 (0.44) KDM4ELMNAMAPTHTTALDH1A1
SCHEMBL24656306 0.64 HTR1A (0.39) ALDH1A1CA2RBP4
SCHEMBL28050747 0.63 OPRM1 (0.44) KDM4ELMNAMAPTHTTALDH1A1
SCHEMBL15079238 0.63 BRPF1 (0.38) MAPTCA2KMT2AMEN1RBP4
SCHEMBL24866846 0.63 MGLL (0.41) KDM4ELMNAMAPTHTTALDH1A1
SCHEMBL9591238 0.63 LMNA (0.50) KDM4ELMNAMAPTHTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119118900-B Method for synthesizing 3-fluorooxindole compound by visible light catalysis NANJING TECH UNIVERSITY (CN) 2026-05-26 CN disclosed
CN-119118900-A Method for synthesizing 3-fluorooxindole compound by visible light catalysis 南京工业大学 2024-12-13 CN disclosed