Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.38 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL312712 | 0.89 | HPGD (0.43) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL311994 | 0.87 | KMT2A (0.46) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL311700 | 0.84 | ALDH1A1 (0.41) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL312527 | 0.83 | MEN1 (0.46) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL311335 | 0.82 | NLRP3 (0.40) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL313232 | 0.81 | HPGD (0.46) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL312241 | 0.79 | ALDH1A1 (0.43) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL312016 | 0.79 | HPGD (0.51) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL311421 | 0.78 | MEN1 (0.42) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL312303 | 0.76 | TUBB4A (0.40) | MEN1KMT2AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093273-B2 | Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2012-01-10 | — | — | US | disclosed |
| EP-2332527-A2 | Flavanoids and Isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2011-06-15 | — | — | EP | disclosed |