Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PPIA | P62937 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23290956 | 1.00 | POLB (0.36) | POLBMAPTTSHRKMT2AHDAC3 | |
| SCHEMBL9396561 | 0.75 | CYP1A2 (0.46) | POLBMAPTTSHRKMT2AHDAC3 | |
| SCHEMBL16328281 | 0.74 | POLB (0.50) | POLBMAPTTSHRKMT2AHDAC3 | |
| SCHEMBL12401091 | 0.70 | ALDH1A1 (0.48) | POLBMAPTTSHRKMT2AHDAC3 | |
| SCHEMBL23730549 | 0.70 | POLB (0.42) | POLBMAPTTSHRKMT2AHDAC3 | |
| SCHEMBL248995 | 0.70 | KMT2A (0.48) | KMT2A | |
| SCHEMBL5824559 | 0.69 | ALOX15 (0.55) | MAPTKMT2AGAAMEN1 | |
| SCHEMBL9396604 | 0.69 | CYP1A2 (0.54) | POLBMAPTTSHRCYP1A2GAA | |
| SCHEMBL4126150 | 0.67 | MAPT (0.41) | MAPTTSHRKMT2AHDAC3HDAC4 | |
| SCHEMBL895388 | 0.66 | HTR2A (0.38) | POLBMAPTTSHRKMT2AHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112805280-B | Heteroaryl compounds for the treatment of huntington's disease | PTC医疗公司 | 2024-12-06 | — | — | CN | disclosed |