Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 6/20 | 0.33 |
| ▸ | MBOAT4 | Q96T53 | 3/20 | 0.33 |
| ▸ | F7 | P08709 | 3/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3130706 | 0.80 | AAK1 (0.39) | PDE4BLMNAMEN1MAPTMAPK1 | |
| SCHEMBL3129614 | 0.76 | PDE4B (0.40) | PDE4BLMNAMEN1MAPTMAPK1 | |
| SCHEMBL3200134 | 0.73 | SLC6A2 (0.43) | PDE4BLMNAMAPTMAPK1KMT2A | |
| SCHEMBL3131252 | 0.73 | ATM (0.41) | PDE4BLMNAMEN1MAPTMAPK1 | |
| SCHEMBL3201429 | 0.72 | PDE4B (0.38) | PDE4BLMNAMEN1MAPTMAPK1 | |
| SCHEMBL3129664 | 0.71 | MAPT (0.41) | PDE4BLMNAMEN1MAPTMAPK1 | |
| SCHEMBL16951534 | 0.70 | RAB9A (0.40) | PDE4BLMNAMEN1MAPTMAPK1 | |
| SCHEMBL16956686 | 0.69 | MAPT (0.46) | PDE4BLMNAMEN1MAPTMAPK1 | |
| SCHEMBL3129261 | 0.69 | AAK1 (0.39) | LMNAMEN1MAPTMAPK1KMT2A | |
| SCHEMBL1143506 | 0.68 | PDE4B (0.51) | PDE4BLMNAMEN1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010003084-A2 | PHOSPHODIESTERASE 4 INHIBITORS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-01-07 | — | — | WO | disclosed |