Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4-Hydroxyisolonchocarpin SCHEMBL13535456 | 0.82 | XDH (0.81) | XDHPTPN1ALOX5MEN1LMNA | |
| Lespeol SCHEMBL5522457 | 0.82 | PTPN1 (0.69) | PTPN1PDE4DCTSKDHODHALOX5 | |
| SCHEMBL29775511 | 0.80 | PTPN1 (0.51) | PTPN1CTSKDHODHALOX5PTGS1 | |
| Cordiachromene A SCHEMBL9356402 | 0.78 | PTGS1 (0.68) | XDHPTPN1PDE4DCTSKALOX5 | |
| Cordiachromene A SCHEMBL16666288 | 0.78 | PTGS1 (0.68) | XDHPTPN1PDE4DCTSKALOX5 | |
| Cordiachromene A SCHEMBL16666262 | 0.78 | PTGS1 (0.68) | XDHPTPN1PDE4DCTSKALOX5 | |
| SCHEMBL10536271 | 0.77 | PTGS1 (0.60) | XDHPTPN1PDE4DCTSKALOX5 | |
| SCHEMBL16244637 | 0.75 | ALOX5 (0.55) | PTPN1CTSKALOX5MEN1LMNA | |
| SCHEMBL16244639 | 0.75 | ALOX5 (0.55) | PTPN1CTSKALOX5MEN1LMNA | |
| SCHEMBL19960677 | 0.75 | XDH (0.80) | XDHPTPN1MAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119074703-A | Application of chalcone compounds in preparation of anti-ischemic cerebral apoplexy drugs | 暨南大学 | 2024-12-06 | — | — | CN | disclosed |