Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.80 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | ACHE | P22303 | 2/20 | 0.54 |
| ▸ | ODC1 | P11926 | 2/20 | 0.54 |
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | BACE1 | P56817 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4-Hydroxyisolonchocarpin SCHEMBL13535456 | 0.92 | XDH (0.81) | XDHPTPN1ALDH1A1CYP3A4HPGD | |
| SCHEMBL13534948 | 0.84 | XDH (0.76) | XDHPTPN1ALDH1A1CYP3A4HPGD | |
| SCHEMBL30383083 | 0.79 | PTPN1 (1.00) | XDHPTPN1ALDH1A1CYP3A4HPGD | |
| SCHEMBL19960678 | 0.78 | PTPN1 (0.85) | PTPN1ACHEODC1BCHEBACE1 | |
| SCHEMBL25296934 | 0.76 | MAPT (0.61) | XDHPTPN1ALDH1A1CYP3A4HPGD | |
| SCHEMBL31297038 | 0.75 | XDH (0.57) | XDHPTPN1ALDH1A1CYP3A4HPGD | |
| Demethylencecalin SCHEMBL31238098 | 0.75 | ALDH1A1 (1.00) | XDHPTPN1ALDH1A1CYP3A4HPGD | |
| Demethylencecalin SCHEMBL29903823 | 0.75 | ALDH1A1 (1.00) | XDHPTPN1ALDH1A1CYP3A4HPGD | |
| Chromene SCHEMBL6271733 | 0.70 | PTPN1 (0.65) | XDHPTPN1ALDH1A1CYP3A4HPGD | |
| Chromene SCHEMBL29644881 | 0.70 | PTPN1 (0.65) | XDHPTPN1ALDH1A1CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180071180-A1 | COMPOSITION OF MATERIALS CONTAINING FLUORIDE VARNISH AND ANTIBACTERIAL AGENTS FOR PREVENTION AND TREATMENT OF DENTAL CARIES | WONKWANG UNIVERSITY CENTER FOR INDUSTRY-ACADEMY COOPERATION (KR) | 2018-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180071180-A1 | COMPOSITION OF MATERIALS CONTAINING FLUORIDE VARNISH AND ANTIBACTERIAL AGENTS FOR PREVENTION AND TREATMENT OF DENTAL CARIES | RAB35, GANC, GALE | XDH 227/4885PTPN1 4504/4885ALDH1A1 3874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.