Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 17/20 | 0.39 |
| ▸ | THRB | P10828 | 17/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3141255 | 0.89 | THRA (0.38) | THRATHRBPPARG | |
| SCHEMBL3910551 | 0.89 | THRA (0.41) | THRATHRBPPARG | |
| SCHEMBL3145982 | 0.84 | THRB (0.40) | THRATHRBPPARG | |
| SCHEMBL3141253 | 0.82 | ALDH1A1 (0.40) | THRATHRB | |
| SCHEMBL3136292 | 0.80 | THRA (0.46) | THRATHRB | |
| SCHEMBL4556497 | 0.80 | THRA (0.41) | THRATHRB | |
| SCHEMBL3137326 | 0.79 | CA12 (0.38) | THRATHRB | |
| SCHEMBL14385501 | 0.78 | THRB (0.37) | THRATHRBPPARG | |
| SCHEMBL3911699 | 0.78 | KMT2A (0.40) | THRATHRB | |
| SCHEMBL5077533 | 0.77 | THRB (0.43) | THRATHRBPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100004271-A1 | HETEROCYCLIC COMPOUNDS AS AGANIST FOR THE THYROID RECEPTOR | KARO BIO AB (SE) | 2010-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100004271-A1 | HETEROCYCLIC COMPOUNDS AS AGANIST FOR THE THYROID RECEPTOR | TSHR, GHSR, TRHR | THRA 4/4885THRB 6/4885PPARG 48/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.