Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20786879 | 0.85 | TNF (0.51) | TNFALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL20037218 | 0.83 | TDP1 (0.53) | ALDH1A1HTTMAPTMEN1KMT2A | |
| SCHEMBL31306252 | 0.81 | ITGB3 (0.51) | ALDH1A1MEN1KMT2AUSP2KDM4E | |
| SCHEMBL5143014 | 0.80 | KMO (0.55) | ALDH1A1HTTMAPTHSD17B10MEN1 | |
| SCHEMBL29958540 | 0.80 | KMO (0.55) | ALDH1A1HTTMAPTHSD17B10MEN1 | |
| SCHEMBL31743124 | 0.79 | DDR1 (0.44) | TNFALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL18955878 | 0.77 | PSMB1 (0.58) | TNFALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL22404777 | 0.77 | PSMB1 (0.47) | TNFALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL30711650 | 0.76 | KMO (0.56) | ALDH1A1HTTHSD17B10MEN1KMT2A | |
| SCHEMBL29174301 | 0.76 | KMO (0.56) | ALDH1A1HTTHSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4734979-A2 | TMEM175 AGONISTS, COMPOSITIONS, AND METHODS OF USE | Caraway Therapeutics, Inc. (US) | 2026-05-06 | — | — | EP | disclosed |
| WO-2025006723-A2 | TMEM175 AGONISTS, COMPOSITIONS, AND METHODS OF USE | CARAWAY THERAPEUTICS, INC. (US) | 2025-01-02 | — | — | WO | disclosed |