Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.54 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.51 |
| ▸ | ACLY | P53396 | 1/20 | 0.49 |
| ▸ | NAAA | Q02083 | 2/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 2/20 | 0.46 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.46 |
| ▸ | TDP2 | O95551 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9061902 | 1.00 | KIF11 (0.54) | KIF11CYP17A1ACLYNAAAPDGFRB | |
| SCHEMBL31128553 | 0.85 | AR (0.51) | KDM1AALDH1A1RAB9AAR | |
| SCHEMBL313099 | 0.85 | AR (0.51) | KDM1AALDH1A1RAB9AAR | |
| SCHEMBL9464193 | 0.83 | CYP17A1 (0.61) | CYP17A1PDGFRBPDGFRAKDM1ATDP2 | |
| SCHEMBL13802320 | 0.81 | AR (0.50) | KIF11ACLYPDGFRBPDGFRAKDM1A | |
| SCHEMBL16945932 | 0.81 | PTGS2 (0.47) | KIF11ACLYPDGFRBPDGFRAKDM1A | |
| SCHEMBL15420520 | 0.81 | ALDH1A1 (0.47) | PDGFRBPDGFRAKDM1API4KBMEN1 | |
| SCHEMBL15605813 | 0.80 | CYP17A1 (0.58) | CYP17A1NAAAPDGFRBPDGFRATDP2 | |
| SCHEMBL8883091 | 0.79 | ACLY (0.49) | KIF11ACLYKDM1AALPLALDH1A1 | |
| SCHEMBL7283993 | 0.79 | KIF11 (0.58) | KIF11ACLYAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |