Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.31 |
| ▸ | RAF1 | P04049 | 2/20 | 0.31 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | CFTR | P13569 | 1/20 | 0.30 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25226760 | 0.80 | CFTR (0.46) | MAPK1KMT2AMEN1NOTUMCFTR | |
| SCHEMBL30595863 | 0.80 | CFTR (0.46) | MAPK1KMT2AMEN1NOTUMCFTR | |
| SCHEMBL26742425 | 0.74 | AGBL2 (0.39) | MAPK1KMT2AMEN1L3MBTL1AGBL2 | |
| SCHEMBL29488332 | 0.73 | ASPH (0.44) | KMT2AMEN1L3MBTL1AGBL2ALDH1A1 | |
| SCHEMBL23012611 | 0.73 | ASPH (0.44) | KMT2AMEN1L3MBTL1AGBL2ALDH1A1 | |
| SCHEMBL29921698 | 0.70 | KMT2A (0.51) | KMT2AAGBL2ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL30661365 | 0.70 | L3MBTL1 (0.38) | KMT2AMEN1RAF1L3MBTL1AGBL2 | |
| SCHEMBL26621180 | 0.70 | L3MBTL1 (0.38) | KMT2AMEN1RAF1L3MBTL1AGBL2 | |
| SCHEMBL31312487 | 0.69 | CFTR (0.39) | MAPK1NOTUMCFTRALDH1A1MAPT | |
| SCHEMBL30595875 | 0.68 | ALDH1A1 (0.36) | AGBL2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4727921-A1 | DUAL RAF AND TUBULIN INHIBITORS AND METHODS OF USE THEREOF | Deciphera Pharmaceuticals, LLC (US) | 2026-04-22 | — | — | EP | disclosed |
| EP-4727922-A1 | DUAL RAF AND TUBULIN INHIBITORS AND METHODS OF USE THEREOF | Deciphera Pharmaceuticals, LLC (US) | 2026-04-22 | — | — | EP | disclosed |
| WO-2024263460-A1 | DUAL RAF AND TUBULIN INHIBITORS AND METHODS OF USE THEREOF | DECIPHERA PHARMACEUTICALS, LLC (US) | 2024-12-26 | — | — | WO | disclosed |
| WO-2024258917-A1 | DUAL RAF AND TUBULIN INHIBITORS AND METHODS OF USE THEREOF | DECIPHERA PHARMACEUTICALS, LLC (US) | 2024-12-19 | — | — | WO | disclosed |