Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 known ✓ | P08173 | 1/20 | 0.35 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8151452 | 0.98 | TSHR (0.47) | TSHRALDH1A1CYP1A2CYP2D6CYP2C19 | |
| Bromide SCHEMBL30082511 | 0.91 | TDP1 (0.48) | TSHRALDH1A1CYP1A2CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL4895935 | 0.88 | TDP1 (0.51) | TSHRALDH1A1CYP1A2CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL8145612 | 0.84 | CA1 (0.43) | TSHRALDH1A1POLBAPEX1HTT | |
| SCHEMBL235139 | 0.79 | MTNR1A (0.49) | TSHRCYP1A2CYP2D6POLBAPEX1 | |
| Hydrochloric Acid SCHEMBL8153299 | 0.77 | TDP1 (0.43) | TSHRALDH1A1CYP1A2POLBAPEX1 | |
| Bromide SCHEMBL28628100 | 0.76 | ALDH1A1 (0.47) | TSHRALDH1A1CYP1A2CYP2D6CYP2C19 | |
| Benzene SCHEMBL28145673 | 0.75 | THRB (0.65) | TSHRALDH1A1POLBAPEX1HTT | |
| SCHEMBL13801021 | 0.75 | HPGD (0.44) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL15901492 | 0.75 | TDP1 (0.50) | TSHRPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122060110-A | Polymerizable organic-inorganic hybrid flexible gel scintillator material and preparation method and application thereof | 福州大学 | 2026-05-19 | — | — | CN | claimed |
| CN-122060110-A | Polymerizable organic-inorganic hybrid flexible gel scintillator material and preparation method and application thereof | 福州大学 | 2026-05-19 | — | — | CN | disclosed |
| CN-119039517-A | Quaternary phosphonium salt eugenol ester polymer antibacterial material and synthetic method thereof | 西北师范大学 | 2024-11-29 | — | — | CN | disclosed |