Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL42893 | 0.79 | HCAR2 (0.51) | TDP1POLBAPEX1HTTALDH1A1 | |
| Hydrochloric Acid SCHEMBL8151452 | 0.78 | TSHR (0.47) | TDP1POLBAPEX1HTTALDH1A1 | |
| SCHEMBL235139 | 0.78 | MTNR1A (0.49) | TDP1POLBAPEX1HTTTHRB | |
| Methane SCHEMBL4468486 | 0.78 | HCAR2 (0.50) | TDP1POLBAPEX1HTTALDH1A1 | |
| Bromide SCHEMBL31315837 | 0.77 | TSHR (0.46) | TDP1POLBAPEX1HTTALDH1A1 | |
| Methacrylic Acid SCHEMBL8131805 | 0.76 | HCAR2 (0.49) | TDP1POLBAPEX1HTTALDH1A1 | |
| SCHEMBL27973892 | 0.76 | HCAR2 (0.49) | TDP1POLBAPEX1HTTALDH1A1 | |
| SCHEMBL148938 | 0.76 | LMNA (0.60) | TDP1POLBAPEX1HTTALDH1A1 | |
| SCHEMBL9418501 | 0.75 | POLB (0.40) | TDP1POLBAPEX1HTTALDH1A1 | |
| SCHEMBL13234390 | 0.75 | ALDH1A1 (0.66) | TDP1HTTALDH1A1TSHRELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080885-A | Process for preparing a phosphonium salt compound having an acryl group | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 2000-06-27 | — | — | US | disclosed |