Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.34 |
| ▸ | MYC | P01106 | 2/20 | 0.34 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31316765 | 0.78 | F2 (0.44) | MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL31316889 | 0.71 | PMM2 (0.44) | MEN1KMT2AKEAP1 | |
| SCHEMBL5958591 | 0.71 | ADORA3 (0.44) | KMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL29571936 | 0.71 | ADORA3 (0.44) | KMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL188296 | 0.69 | MEN1 (0.65) | MEN1KMT2ASMN1; SMN2KEAP1KDM4E | |
| SCHEMBL30598338 | 0.68 | SMN1; SMN2 (0.55) | MEN1KMT2ASMN1; SMN2KEAP1KDM4E | |
| SCHEMBL538290 | 0.68 | SMN1; SMN2 (0.55) | MEN1KMT2ASMN1; SMN2KEAP1KDM4E | |
| SCHEMBL403403 | 0.67 | MEN1 (0.49) | MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL15639447 | 0.67 | MGLL (0.37) | MEN1KMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL29571794 | 0.67 | MGLL (0.37) | MEN1KMT2ASMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743453-A1 | MODULATORS OF MITOCHONDRIAL DNA REPLICATION | Pretzel Therapeutics, Inc. (US) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025015178-A1 | MODULATORS OF MITOCHONDRIAL DNA REPLICATION | PRETZEL THERAPEUTICS, INC. (US) | 2025-01-16 | — | — | WO | disclosed |