Sugi Predict

Sugi Predict / Compounds / SCHEMBL3131783

SCHEMBL3131783

SCHEMBL3131783

NC(=O)Cc1ccc(F)c([N+](=O)[O-])c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 5/20 0.54
▸ RECQL P46063 1/20 0.54
▸ ALDH1A1 P00352 3/20 0.52
▸ MEN1 O00255 3/20 0.52
▸ KMT2A Q03164 3/20 0.52
▸ HIF1A Q16665 1/20 0.50
▸ VCAM1 P19320 1/20 0.47
▸ MAPT P10636 2/20 0.44
▸ HTT P42858 1/20 0.44
▸ SMN1; SMN2 Q16637 1/20 0.44
▸ ABL1 P00519 2/20 0.43
▸ BCR P11274 2/20 0.43
▸ CA2 P00918 1/20 0.42
▸ CA1 P00915 1/20 0.41
▸ MMP2 P08253 1/20 0.41
▸ CA14 Q9ULX7 1/20 0.41
▸ GRM8 O00222 1/20 0.41
▸ GRM6 O15303 1/20 0.41
▸ GRM4 Q14833 1/20 0.41
▸ NPSR1 Q6W5P4 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30783383 1.00 LMNA (0.54) LMNARECQLALDH1A1MEN1KMT2A
SCHEMBL29902892 0.87 ATM (0.51) LMNARECQLALDH1A1MEN1KMT2A
SCHEMBL28847424 0.87 ATM (0.51) LMNARECQLALDH1A1MEN1KMT2A
SCHEMBL2656422 0.85 LMNA (0.53) LMNARECQLALDH1A1MEN1KMT2A
SCHEMBL2648717 0.85 LMNA (0.53) LMNARECQLALDH1A1MEN1KMT2A
SCHEMBL4684043 0.85 CASP6 (0.49) LMNAALDH1A1MAPTHTTCA2
SCHEMBL5362455 0.84 LMNA (0.52) LMNARECQLALDH1A1MEN1KMT2A
SCHEMBL2339087 0.84 LMNA (0.55) LMNARECQLALDH1A1MEN1KMT2A
SCHEMBL7252708 0.84 LMNA (0.52) LMNARECQLALDH1A1MEN1KMT2A
SCHEMBL2742575 0.82 MAPT (0.58) LMNAALDH1A1MAPTSMN1; SMN2CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11969425-B2 Inhibitor of indoleamine-2,3-dioxygenase (IDO) INVENTISBIO LLC (US) 2024-04-30 — — US disclosed
CN-113896685-B Indoleamine-2, 3-dioxygenase (IDO) inhibitors 益方生物科技(上海)股份有限公司 2024-02-06 — — CN disclosed
US-20230338373-A1 INHIBITOR OF INDOLEAMINE-2,3-DIOXYGENASE (IDO) INVENTISBIO LLC 2023-10-26 — — US disclosed
EP-3414224-B1 INHIBITOR OF INDOLEAMINE-2,3-DIOXYGENASE (IDO) INVENTISBIO LLC (US) 2022-03-23 — — EP disclosed
US-20220054486-A1 INHIBITOR OF INDOLEAMINE-2,3-DIOXYGENASE (IDO) INVENTISBIO LLC (US) 2022-02-24 — — US disclosed
CN-113896685-A Indoleamine-2, 3-dioxygenase (IDO) inhibitors 益方生物科技(上海)股份有限公司 2022-01-07 — — CN disclosed
US-10980807-B2 Inhibitor of indoleamine-2,3-dioxygenase (IDO) INVENTISBIO LLC (US) 2021-04-20 — — US disclosed
US-20200046697-A1 INHIBITOR OF INDOLEAMINE-2,3-DIOXYGENASE (IDO) INVENTISBIO LLC 2020-02-13 — — US disclosed
EP-3414224-A1 INHIBITOR OF INDOLEAMINE-2,3-DIOXYGENASE (IDO) Inventisbio Inc. (KY) 2018-12-19 — — EP disclosed
WO-2017139414-A1 INHIBITOR OF INDOLEAMINE-2,3-DIOXYGENASE (IDO) INVENTISBIO INC. (KY) 2017-08-17 — — WO disclosed
US-7686850-B2 Nitrosulfide dyes CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-03-30 — — US disclosed
US-20090130045-A1 Nitrosulfide dyes CIBA SPECIALTY CHEMICALS CORP. 2009-05-21 — — US disclosed
US-20090100610-A1 Mixture of Sulfide Dyes CIBA CORPORATION 2009-04-23 — — US disclosed
CN-101326246-A Mixture of sulfide dyes CIBA SC HOLDING AG (CH) 2008-12-17 — — CN disclosed
EP-1937780-A2 MIXTURE OF SULFIDE DYES Ciba Holding Inc. (CH) 2008-07-02 — — EP disclosed
CN-101203573-A Nitrosulfide dyes CIBA SC HOLDING AG (CH) 2008-06-18 — — CN disclosed
EP-1893697-A2 NITROSULFIDE DYES CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) 2008-03-05 — — EP disclosed
WO-2006136617-A2 MIXTURE OF SULFIDE DYES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-12-28 — — WO disclosed
WO-2006136518-A2 NITROSULFIDE DYES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-12-28 — — WO disclosed
WO-2003099242-A1 COSMETIC AGENTS CONTAINING PROTEIN DISULFIDE ISOMERASE HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-12-04 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230338373-A1 INHIBITOR OF INDOLEAMINE-2,3-DIOXYGENASE (IDO) IDO1, IDO2, INMT LMNA 4749/4885RECQL 1256/4885ALDH1A1 801/4885
US-20090100610-A1 Mixture of Sulfide Dyes KRT18, TST, ARSA LMNA 2959/4885RECQL 4000/4885ALDH1A1 360/4885
US-11969425-B2 Inhibitor of indoleamine-2,3-dioxygenase (IDO) IDO1, IDO2, INMT LMNA 4749/4885RECQL 1256/4885ALDH1A1 801/4885
US-20220054486-A1 INHIBITOR OF INDOLEAMINE-2,3-DIOXYGENASE (IDO) IDO1, IDO2, INMT LMNA 4749/4885RECQL 1256/4885ALDH1A1 801/4885
US-20200046697-A1 INHIBITOR OF INDOLEAMINE-2,3-DIOXYGENASE (IDO) IDO1, IDO2, INMT LMNA 4749/4885RECQL 1256/4885ALDH1A1 801/4885
US-20090130045-A1 Nitrosulfide dyes C5, NOX5, C3AR1 LMNA 1304/4885RECQL 711/4885ALDH1A1 881/4885
US-10980807-B2 Inhibitor of indoleamine-2,3-dioxygenase (IDO) IDO1, IDO2, INMT LMNA 4749/4885RECQL 1256/4885ALDH1A1 801/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.