Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.40 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.40 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 4/20 | 0.37 |
| ▸ | HTR1B | P28222 | 3/20 | 0.37 |
| ▸ | HTR1F | P30939 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30886293 | 0.71 | PI4KA (0.52) | PI4KAPI4K2BPI4K2API4KBALOX15 | |
| SCHEMBL4004688 | 0.71 | HRH4 (0.45) | HTR1DHTR1BHTR1FHTR1A | |
| SCHEMBL20265805 | 0.71 | HTR1D (0.44) | HTR1DHTR1BHTR1FALOX15LRRK2 | |
| SCHEMBL25320978 | 0.68 | PI4KA (0.49) | PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL24304702 | 0.67 | TRPC6 (0.46) | HTR1DHTR1BHTR1FALOX15LRRK2 | |
| SCHEMBL17967804 | 0.67 | HTT (0.41) | HTR1DHTR1BHTR1FLRRK2SMN1; SMN2 | |
| SCHEMBL20919392 | 0.67 | TRPC6 (0.57) | — | |
| SCHEMBL2320740 | 0.66 | HRH4 (0.40) | HTR1DHTR1BHTR1FALOX15LRRK2 | |
| SCHEMBL18154726 | 0.66 | ALDH1A1 (0.41) | HTR1DHTR1BHTR1FHTR1A | |
| SCHEMBL30788216 | 0.66 | HTR1B (0.42) | HTR1DHTR1BHTR1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250059188-A1 | ARYLSULPHONAMIDE COMPOUNDS | Anaxis Pharma Pty Ltd (AU) | 2025-02-20 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250059188-A1 | ARYLSULPHONAMIDE COMPOUNDS | MLKL, CASP1, CASP9 | PI4KA 847/4885PI4K2B 1306/4885PI4K2A 1708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.