SCHEMBL31319033

SCHEMBL31319033

C[C@H](Oc1cc(B2OC(C)(C)C(C)(C)O2)ccc1NS(=O)(=O)C(F)F)c1ccccc1F

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ SCN1A P35498 9/20 0.38
▸ SCN5A Q14524 9/20 0.38
▸ SCN8A Q9UQD0 9/20 0.38
▸ CA1 P00915 4/20 0.35
▸ CA2 P00918 4/20 0.35
▸ CA9 Q16790 4/20 0.35
▸ CA12 O43570 1/20 0.34
▸ CA3 P07451 1/20 0.34
▸ CA4 P22748 1/20 0.34
▸ CA6 P23280 1/20 0.34
▸ CA5A P35218 1/20 0.34
▸ CA7 P43166 1/20 0.34
▸ CA14 Q9ULX7 1/20 0.34
▸ CA5B Q9Y2D0 1/20 0.34
▸ SLC6A4 P31645 1/20 0.34
▸ ROCK1 Q13464 1/20 0.33
▸ IGLV6-57 P01721 1/20 0.32
▸ LPL P06858 2/20 0.31
▸ LIPG Q9Y5X9 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25706773 1.00 SCN1A (0.38) SCN1ASCN5ASCN8ACA1CA2
SCHEMBL31319010 0.85 CYP19A1 (0.41) CA1CA2CA9CA12CA3
SCHEMBL25706902 0.85 CYP19A1 (0.41) CA1CA2CA9CA12CA3
SCHEMBL24133485 0.84 LPL (0.39) CA1CA2CA9CA12CA3
SCHEMBL25313255 0.84 LPL (0.39) CA1CA2CA9CA12CA3
SCHEMBL25288246 0.84 LPL (0.39) CA1CA2CA9CA12CA3
SCHEMBL30408224 0.84 LPL (0.39) CA1CA2CA9CA12CA3
SCHEMBL25706906 0.82 CA1 (0.35) CA1CA2CA9CA12CA3
SCHEMBL31319099 0.82 CA1 (0.35) CA1CA2CA9CA12CA3
SCHEMBL31319039 0.81 SLC6A4 (0.36) SCN1ASCN5ASCN8ACA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250115598-A1 BIFUNCTIONAL ARYLSULPHONAMIDE COMPOUNDS Anaxis Pharma Pty Ltd (AU) 2025-04-10 — — US disclosed
US-20250059188-A1 ARYLSULPHONAMIDE COMPOUNDS Anaxis Pharma Pty Ltd (AU) 2025-02-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250115598-A1 BIFUNCTIONAL ARYLSULPHONAMIDE COMPOUNDS MLKL, CASP1, CASP9 SCN1A 2518/4885SCN5A 3362/4885SCN8A 3450/4885
US-20250059188-A1 ARYLSULPHONAMIDE COMPOUNDS MLKL, CASP1, CASP9 SCN1A 1078/4885SCN5A 1874/4885SCN8A 1799/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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