Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 3/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 4/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.37 |
| ▸ | SRC | P12931 | 2/20 | 0.37 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.37 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.37 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31032943 | 0.82 | SIGMAR1 (0.41) | ABL1KDREGFRERBB2SIGMAR1 | |
| SCHEMBL31032965 | 0.81 | KDR (0.41) | ABL1KDREGFRERBB2SIGMAR1 | |
| SCHEMBL1439729 | 0.79 | KDM4E (0.40) | EGFR | |
| SCHEMBL31032954 | 0.78 | GAA (0.43) | ABL1KDREGFRERBB2SIGMAR1 | |
| SCHEMBL31320113 | 0.76 | KDR (0.36) | ABL1KDREGFRERBB2SIGMAR1 | |
| SCHEMBL23396651 | 0.73 | MAPT (0.31) | — | |
| SCHEMBL31320125 | 0.71 | ABL1 (0.44) | ABL1FGFR1SRCJAK2JAK1 | |
| SCHEMBL31320131 | 0.70 | ABL1 (0.44) | ABL1FGFR1SRCJAK2JAK1 | |
| SCHEMBL1440229 | 0.69 | PDPK1 (0.37) | TYK2 | |
| SCHEMBL31320136 | 0.69 | GAA (0.51) | ABL1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024240108-A1 | ARYL UREA PARP1 INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 上海海和药物研究开发股份有限公司 | 2024-11-28 | — | — | WO | disclosed |